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Stress-tolerance of plants involves the activation of cascades of molecular networks leading to expression of stress-related enzymes

3.6 Anti-muscular atrophy Muscular atrophy is characterized by disrupted molecular pathways such as non-physiological Hedgehog (Hh) signaling, dysfunctional AKT signaling and dysregulation of ubiquitin-proteasome to overall cellular protein turnover, resulting in upregulated components of the ubiquitin-proteasome pathway, specifically muscle atrophy F-box (MAFbx/atrogin-1) and muscle ring finger 1, that promote proteolytic degradation

Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, et al