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10.1523/JNEUROSCI.3903-07.2007 J

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There are currently two common approaches to the timing of cleft palate repair in North America: (a) two-stage repair, with the soft palate repair and veloplasty performed at the time of lip adhesion or primary lip repair, and the hard palate repaired before 18 months, or delayed further with the use of an obturator

All patients were first treated with a low-calorie diet (total energy intake 1,200-1,400 kcal/day) in a run-in period lasting up to 12 weeks

The authors reported that although 97% of the portal vein samples were positive for endotoxin as measured by a Limulus bioassay, only 9% of the patients had gut flora culturable from the portal vein