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What clinicians watched in trials Resting heart rate and blood pressure at baseline, then at regular intervals

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Quick Answer: The thigh is a recommended Wegovy injection site because it contains adequate subcutaneous fatty tissue for proper drug absorption and offers a large, easily accessible surface area for safe self-administration

The TGA cited several key factors: Lack of Robust Clinical Evidence: While preclinical and animal studies show promise, there is a distinct lack of large-scale, high-quality human clinical trials to establish safety and efficacy for various claimed uses

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Many participants also experienced improvements in: Waist circumference Blood pressure Blood glucose Physical functioning Quality of life measures SELECT Trial The SELECT cardiovascular outcomes trial investigated semaglutide in adults with overweight or obesity and established cardiovascular disease