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Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig

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[] Depressive disorders, psychosis, bipolar illness and autism spectrum disorder (ASD) are all associated with mitochondrial abnormalities

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