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Experiments conducted using a polyacrylamide-based microchannel device that allows independent control of substrate stiffness and channel dimensions revealed that optimal migration of triple-negative MDA-MB-231 and SUM159 human breast cancer cells occurs at intermediate stiffness [90]

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83 A very recent study presents the trans-sulphuration pathway as being directly beneficial for cancer cells to maintain the redox equilibrium and evade ferroptosis, as, upon inhibition of cysteine import, glutathione synthesis is supplied by cysteine derived from the trans-sulphuration pathway

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Animals were administered with either TAT or TAT-DAT NT (at the dose of 0.4 nmol