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This supports the hypothesis that ciliopathies, such as BBS, involve intrinsic defects in leptin and insulin pathways that are exacerbated, rather than solely caused, by obesity

New fat-burning diabetes pill protects muscle and appetite Date: December 7, 2025 Source: Karolinska Institutet Summary: Researchers have developed a new oral drug that boosts metabolic activity in muscle rather than altering appetite like GLP-1 drugs

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