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So let me give you a clear, honest, evidence-based look at what we actually know, what remains uncertain, and what I tell my patients when they ask about it

Gastrointestinal effects: Retatrutide, like other GLP-1 receptor agonists, commonly causes nausea, vomiting, and reduced appetite, as documented in the SmPCs for licensed GLP-1-based medicines such as semaglutide and tirzepatide

"Unknown risk with no proven benefit" is the opposite of a good research design