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Table of Contents Nausea as a Side Effect of Retatrutide How Common Is Nausea During Treatment Why Retatrutide May Cause Digestive Symptoms Managing Nausea and When to Seek Medical Advice What the Current Clinical Evidence Shows Talking to Your GP or Prescriber About Side Effects Scientific References Frequently Asked Questions Nausea as a Side Effect of Retatrutide Nausea is one of the most frequently reported side effects of retatrutide in clinical trials, consistent with the GLP-1 receptor agonist class, and is generally dose-dependent and most pronounced during dose escalation

GLP-1, oxyntomodulin, and the clinically used mimetic exendin-4 are among the most extensively studied GLP-1R peptide agonists in functional and structurefunction studies

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Eloralintide has active Phase 3 ENLIGHTEN trials, cagrilintide and CagriSema remain in Phase 3 development, and petrelintide completed the Phase 2 ZUPREME-1 study while Roche and Zealand prepare later-stage development