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When activated, Nrf2 upregulates protective antioxidant enzymes, including superoxide dismutase (SOD2), catalase (CAT), and glutathione peroxidase (GPX1) (Qian et al, 2026)4

E., Burns, A., Selby, A

Thats a technical description, but the owner-facing translation is simple: its part of the system that helps a dog convert fuel into everyday vitality