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CATEGORY 2 SUBSTANCES: Many peptides have been classified by the FDA as Category 2 bulk drug substances under Section 503A, designated as substances that may present significant safety risks

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Earlier shorter trials reported small statistically significant differences but the effect sizes were modest

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For anabolic agents (testosterone) and peptide hormones (hGH) , a request for review and approval must be submitted to The National Center for Drug Free Sport (NCDFS) through the Director of Athletics prior to the use of the medication

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