Pernicious anaemia , an autoimmune condition characterised by antibodies against intrinsic factor or gastric parietal cells, accounts for a significant proportion of cases in the UK
With so many benefits, its clear why B12 is a popular supplement choice
The high blood level isn't what's causing the symptoms
In clinical trials of semaglutide for type 2 diabetes mellitus, patients exposed to semaglutide subcutaneous injection reported increases in amylase (hyperamylasemia) and lipase, and had a mean increase from baseline in amylase of 13% and lipase of 22%
While preclinical studies report associations of interest for metabolic research, human data are absent
After initial correction, some individuals may require ongoing maintenance injections (often monthly) if they cannot adequately absorb B12 from diet or oral supplements