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Any glucose that does enter the alpha cell is assumed to be metabolised (via glucokinase, glycolysis and the Krebs cycle) to produce ATP, which interacts with ATP-sensitive potassium channels (K ATP channels), leading to cell depolarisation and generation of action potentials [32, 33]

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In addition, significant weight is only lost when lifestyle changes have been implemented concurrently alongside the intake of orlistat [123]

[9] Nicotinamide and newer precursors like NR typically do not cause flushing, making them more tolerable for many users

Spitz, D.R

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