flow trial semaglutide kidney outcomes nejm 2024 hazard ratio 0.76 Semaglutides Are Poised to Remake Chronic Disease Care FLOW clinical Trial (funded by

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Circadian factors may influence tolerability and side-effect timing, but not overall weight loss or glycemic benefits based on current clinical evidence

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While these large-scale observational studies are encouraging, more research is needed, including randomized controlled trials to determine whether GLP-1 medications directly reduce substance use, including stimulant use, and improve long-term recovery outcomes

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Cardiovascular Health: Studies have shown that Semaglutide can reduce the risk of major cardiovascular events such as heart attack and stroke in people with type 2 diabetes