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doi: 10.1038/s41591-019-0367-9 233 GuoJYKarsli-UzunbasGMathewRAisnerSCKamphorstJJStroheckerAMet al

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An equivalent amount of plain serum-free medium was added to control cells

Step 5: Add the water down the side of the glass, not directly onto the powder

Collectively, these findings reveal that SHMT1/2 extend far beyond its metabolic origins, functioning as a versatile signaling hub that integrates 1 C metabolism with diverse processes including immune regulation, genome maintenance, and oncogenic transformation