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Gu X, Zhang L, Yuan H, Zhang M

Weight regain is likely without a plan

Recent studies support that COVID-19 has effects beyond the respiratory tract, with vascular complications arising as relevant factors worsening its prognosis, then making patients with previous vascular disease more prone to severity or fatal outcome

Researchers should consider the trial design, reported frequency, severity, discontinuation patterns and any dose-related observations

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Nonetheless, with the exception of certain viral encephalitis and prion disorders [499], such conditions are not fundamentally enigmatic and are less central to current neurodegeneration-focused drug development efforts compared to diseases like AD or frontotemporal lobar degeneration