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and C151 together with a cluster of neighboring basic amino acids (H129, K131, R135, K150, and H154), an NO sensor (59)
Notably, deferred frozen-thawed embryo transfer (FET) may restore synchrony and reset the uterine environment, with studies reporting higher live birth rates and lower miscarriage rates compared to fresh transfer, though clinical routine use requires caution due to heterogeneity in evidence
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Methods Reagents and drugs L-carnitine, H 2 O 2 , MTT, 2',7'-dichlorfluorescein-diacetate (DCFH-DA) and MK886 were purchased from Sigma-Aldrich (St Louis, MO, USA)
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