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Why Mounjaro Can Cause Changes in Stool Colour Mounjaro exerts its therapeutic effects by activating both GLP-1 and GIP receptors, which are found throughout the gastrointestinal tract

Konofagou EE, Luo J, Saluja D, et al

Topline results announced in December 2025 were positive, showing that patients who switched from injectables to oral orforglipron maintained their weight loss

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While there are no strict dietary restrictions with Semaglutide, avoiding or limiting foods and beverages that are known to increase gas production can be helpful

Warmth alone is not an absolute contraindication to continued treatment, but it warrants closer observation during the next injection cycle