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What This Supports: Glutathione peroxidase (GPx) activity: selenium-dependent enzyme required for for neutralizing harmful substances

Spoelstra-de Man AME, Elbers PWG, Oudemans-Van Straaten HM (2018) Vitamin C: should we supplement

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Avoid unregulated or dubious sources, as they may not contain the stated amounts of glutathione or could pose health risks

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Unexpectedly, activation of p21, ICAM1, or SRXN1 was not observed (Supplementary Figure S5), although DNA ( Figure 6 ) is consistent with the lack of activation of an adaptive oxidative stress response pathway observed here and in a previous study ( Figure 7 , AQ-QI and DEAQ-QI exposure resulted in activation of the ER stress response