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As a melanocortin agonist, it activates receptors in the brain that signal sexual interest and arousal before any physical response occurs
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146 The pathophysiology of addiction has been extensively investigated, revealing drug-induced dysregulation of multiple neural circuits and neurochemical systems, including dopamine, opioid peptides, corticotropin-releasing factor, dynorphin, glutamate, and gamma-aminobutyric acid (GABA)
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