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Real-world persistence is low: about half discontinue within a year and roughly three-quarters within two years , often due to cost or side effectsraising the risk of rebound weight and lost health gains (Scientific American on discontinuation rates)

He hasn't seen any essential difference in patients using the branded and compounded forms, although "some people say the compounding is a little less effective," Gupta said

No gap in treatment

GLP-1 levels decrease after perimenopause GLP-1 is the hormone that signals your brain you're full

This matters because injections are a barrier for some patients

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