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Nasal administration of esketamine (Spravato ) was approved by the US Food and Drug Administration (FDA) in 2019 to treat adults with treatment-resistant depression and in 2020 for adults with MDD with acute suicidal ideation or behavior

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The drug has been approved by the U.S

Severe and fatal COVID-19 is characterised by increased circulating glucagon like peptide 1 and procalcitonin modulated by type 2 diabetes

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While they can be effective when used correctly, they also carry potential side effects such as nausea, bloating and fatigue, and they must always be taken under professional supervision