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Neef V, Suma Choorapoikayil, Hof L, Meybohm P, Zacharowski K

An inadequate or excessive compensatory adaptive response, termed malacclimatization, can impair oxygen delivery, leading to hypoxemia, which is defined as a decrease in the arterial partial pressure of oxygen (PaO)

Exclusion Criteria: Pregnancy

Those following weight management programmes

The cardiovascular system is uniquely vulnerable to ferroptotic stress due to its high metabolic demand, elevated oxygen consumption, and dense mitochondrial networks, which together generate substantial reactive oxygen species (ROS)

These ketones are formed from FFA that also increase from about 0.7 mM to about 1.6 mM (Veech, 2006) rather than total ketones