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To clarify the role of PGC-1, SR-18292 (HY-101491) and ZLN005 (HY-17538) were acquired from MedChemExpress (Shanghai, China)

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Briefly, 500 l binding buffer was added to each tube and transferred to a 1.5 ml centrifuge tube (1510 5 cells)

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PIONEER 6 PIONEER 6 was a randomized, double-blind, placebo-controlled trial comparing oral semaglutide to placebo designed to rule out an excess in cardiovascular risk with oral semaglutide among patients with T2DM