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Safety of L-Carnitine Carnitine is relatively well-tolerated but in high doses it may increase levels of trimethylamine-N-oxide (TMAO), a compound linked with an heart disease since it can increase blood pressure and the formation of plaque within the artery walls (atherosclerosis) (9)

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Quantification of hepatic triglycerides Livers were homogenized in triglyceride assay buffer and triglycerides were measured using the Triglyceride quantification Assay Kit (Abcam) according to the manufacturers instructions