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A similar model has previously been used in several species (11-14)

Prevention: Label every vial with the concentration

The contribution of the rotation around dihedral angles to the potential energy was calculated using the following equation: where k is the torsion barrier (rotation barrier), k is the current value of the torsion angle, n is the period (the number of energy minima per one full cycle), and 0 is the standard value of the torsion angle

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