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ESRD Patients on Hemodialysis The recommended starting dose is 10-20 mg/kg dry body weight as a slow 2-3 minute bolus injection into the venous return line after each dialysis session

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However, reaching optimal glycemic control typically requires 12-16 weeks, particularly as the dose is gradually titrated upward according to FDA-approved protocols

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(1996) shows that when GH and IGF-1 are combined, they can significantly counteract weight loss and promote weight gain, particularly in the case of burned rats