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Diabetes and obesity, both of which are associated with the secretion of pro-inflammatory adipokines and the reduced availability of nitric oxide, may lead to the occurrence of HFpEF in young individuals due to myocardial remodeling and fibrosis [7, 34]

Modern nutrition science began about a century ago in the era of Nutrient Deficiency, which has given way to the era of Dietary Excess

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Lactate dehydrogenase activity accelerates HFSC activation and the hair cycle [4]