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The muscle preservation benefits accumulate over time and are most apparent after 8-12 weeks of consistent use combined with resistance training

Gastrointestinal adverse events causing discontinuation occurred in 2.7% of Tirzepatide patients versus 5.6% on Semaglutide

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Additionally, it should be used with caution in patients with a history of gallbladder disease

The pill was approved for chronic weight management in adults with obesity or overweight and at least one related health condition, broadening the potential patient pool at a time when insurers, employers and governments are wrestling with spiraling healthcare costs related to obesity