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J Pain 11(11):11461154 Warncke T, Stubhaug A, Jrum E (1997) Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo

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However, its potential impact on sleep, particularly insomnia, has become a topic of increasing interest and concern

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However, this approach may also increase the risk of gastrointestinal side effects