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The above described process is carried out in a solvent optionally in presence of a coupling agent and/or a base

Research on this connection remains limited

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[0042] In step 4), Alloc in Fmoc-Lys(Alloc)-OH is removed twice using 0.1-0.3 equivalents of Pd(PPh 3 ) 4 and 5-10 equivalents of morpholine or phenylsilane for 10-30 min each time, wherein CH 2 Cl 2 is used as a solvent in the removal