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Exendin-4 protects against hyperglycemia-induced cardiomyocyte pyroptosis via the AMPK-TXNIP pathway

Although this increase is generally considered safe by the FDA and resolves after cessation of treatment, it is still a potential consideration for patient adherence and preference (82)

This data gap means we cannot quantify infant exposure or confirm safety, making the conservative medical approach to avoid these medications during breastfeeding

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