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Muscle glycogen supercompensation is enhanced by prior creatine supplementation
It reduces inflammation in fat tissue to improve insulin sensitivity, enhances insulin signaling
Supplementation of L-carnitine stimulates the latter process and thus helps reduce stored body fat which will lead to rapid weight loss
In endometriosis, macrophages in the peritoneal fluid tend toward the M1 phenotype, perpetuating inflammation and allowing endometrial implants to establish and grow
Recently, the newly developed drug tirzepatide, which targets both the GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, was introduced to the market to treat type 2 diabetes and obesity in 2022 and 2023, respectively (Table 1)