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Similar experimental methods were used to evaluate the glucose homeostasis effect of GLUT1 inhibition in metformin-treated mice

A randomized trial of Iscador in advanced non-small cell lung cancer patients receiving carboplatin-based chemotherapy found that those receiving Iscador were less likely to need a chemotherapy dose reduction and experienced less frequent side effects and hospitalizations (Bar-Sela 2013)

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The characteristic features associated with the tumor microenvironment, like excessive production of ROS [82], elevated carbon dioxide levels [18, 83] and increased response to glucose [82] and N -acetylglucosamine [54, 84], are also responsible for apical extension during hyphae formation in fungi

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