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In vitro , the DPP4 release increased substantially during fat cell differentiation, and comparison with preadipocytes and adipose tissue, macrophages showed that adipocytes most likely represent the major source of DPP4 released from the intact organ to the circulation

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In addition to glycolytic intermediates, TCA cycle intermediates are also used for biosynthetic precursors accumulation

Schumann T, Konig J, Henke C, Willmes DM, Bornstein SR, Jordan J et al (2020) Solute carrier transporters as potential targets for the treatment of metabolic disease