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We invited guest bloggers to comment on the guidelines including two very popular blogs by Bruce Wolffenbuttel: and Alfie Thain: Only One Chance Pernicious Anaemia: A Misnomer

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This seems low, as studies have shown that 2g/day is necessary to increase plasma L-Carnitine levels

Symptoms of Low Thyroid (Hypothyroidism) Reduced body temperature Cool skin Cold hands & feet Reduced appetite Weight gain Constipation Reduced muscle strength and stamina Puffiness of skin, especially in the face Depression Rapid hair loss Elevated cholesterol, and sometimes triglycerides Vitamin B12 deficiency, often due to autoimmune disease In women, ovaries become polycystic, which contributes to PCOS Did you notice the bullet point about cholesterol

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Future studies, particularly longitudinal and mechanistic investigations, are essential to validate these findings and refine diagnostic and therapeutic approaches for optimizing outcomes in congenital hypothyroidism