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I am pleased to announce that I have been accepted into the 2023 Diversity Summer Internship Program (DSIP) at The Johns Hopkins Bloomberg School of Public Health
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Inhibition of glutathione metabolism by BSO decreased the ESCC tumor burden To investigate whether glutathione metabolism contributed to the progression of ESCC development, we treated mice bearing ESCC 20 weeks after initial carcinogen treatment with buthionine sulfoximine (BSO), a commonly used chemical inhibitor of -glutamylcysteine synthetase (-GCS) that decreases tissue glutathione concentrations (Figure 3a)
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In this sense, Met plays a fundamental role in the liver by stimulating the synthesis of very low-density lipoprotein (VLDL), and therefore, helps reduce TAG accumulation (Martinov et al., 2010)
