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It has important roles in the body, contributing to critical processes like energy production, red blood cell formation, DNA synthesis, and neurological function

Using isotope-labeled glucose metabolomics assays, we found that GGCT overexpression significantly promotes glucose influx into the TCA cycle to sustain cell proliferation

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Depleting GSH levels with BSO increased artemisinin sensitivity without affecting heme levels

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The body receives a flat dose, processes it, and the negative feedback loop eventually suppresses endogenous production