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10.1016/j.mce.2021.111171 83 LiT.ZhouL.FanM.ChenZ.YanL.LuH.et al (2022)

Additionally, the "lowers A1C" claim rests on a result that didn't reach statistical significance

When supervised by a physician using FDA-approved medications, the risks are generally lower than standard dosing because side effects are dose-dependent

The Incretin System: A Brief Primer The gut releases two major incretin hormones after a meal: GIP (secreted primarily by duodenal K-cells) and GLP-1 (secreted by ileal L-cells)

While Kurtzeborns experience with semaglutide was relatively rare, her tirzepatide use produced more typical results