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Sci Rep 2019 9:1

Arrazola, J

Brain Imaging Behav

Meanwhile, tumor cells express a mitochondria-targeted variant of SLC1A5 that channels glutamine directly into the organelle, fuelling TCA-cycle anaplerosis and NADPH production

These signals collectively trigger assembly of the NLRP3-ASC-caspase-1 complex, resulting in mature IL-1/IL-18 secretion and gasdermin-D-mediated pyroptosis (101)

Simultaneously, NPY can inhibit the activity of vasodilator substances and enhance vasoconstrictor substances, resulting in a significant increase in vasoconstriction (80)