Elife (2022) 11:e74549
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Mechanistically, RSV enhances spermatogenesis and sperm function primarily via activation of the Sirtuin 1 (SIRT1)/Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway, inhibition of NF-B-mediated inflammation, and regulation of the hypothalamic-pituitarygonadal (HPG) axis
These findings highlight the critical role of stromal-tumor interactions and suggest that targeting miR-432-5p or restoring CHAC1 function could represent promising strategies to overcome chemotherapy resistance in prostate cancer (Zhao et al., 2024)
On the other hand, increasing evidence shows that microbiota regulates the immune response, changes the balance of T cell subsets, affects the absorption of trace elements and thyroid hormone metabolism through the gut-thyroid axis, and finally affects the thyroid function [25, 26]
DOI: Published: Publisher Name: Adis, Singapore Print ISBN: 978-981-10-5310-8 Online ISBN: 978-981-10-5311-5 eBook Packages: MedicineMedicine (R0) Keywords Resilience Pathways High Mobility Group Box Protein (HMGB1) AMP Kinase (AMPK) Nuclear Factor Kappa B (NFkB) Damage-associated Molecular Patterns (DAMPs) These keywords were added by machine and not by the authors
