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Description

This phosphorylation event subsequently activates various substrates, including insulin receptor substrate (IRS) and SRC homology 2 domain-containing protein (SHC), which in turn recruit additional signaling molecules to activate two major intracellular pathways: the phosphoinositide 3-kinase (PI3K)/serine-threonine kinase (AKT) pathway and the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) pathway (Wang J

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However, during the first few months, scalp irritation, itching, dryness, and brief increased shedding are typical side effects

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Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells

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S.MumbrekarK

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Endocrine 65(1):94101

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doi: 10.1097/PAI.0000000000001148 52

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