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P=0.02)

This is adequate for peripheral metabolic effects like appetite suppression and insulin sensitization, but it may limit the full potential of central GLP-1 receptor activation

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[7] The study also demonstrated that older persons (mean age, 61 years) have higher levels of CD38 gene expression than younger adults (mean age, 34 years)

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In one study, intermittent fasting (i.e., alternate-day fasting) alleviated the increase of LPL expression in the brain of a mouse model of AD possibly by mediation of an increase in ketone body levels (i.e., -hydroxybutyrate) subsequent to the induced ketosis [130]