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Human studies have produced mixed results

Its ability to stimulate angiogenesis (via VEGF) raises the question of a potential risk in the context of conditions where neovascularization is undesirable, such as certain cancers

For skin focused goals, topical use is common

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Benefits of subcutaneous administration include: Easier for patients to give themselves injections Less risk of muscle irritation Potential for slower absorption, depending on the injection site Intravenous (IV) Usage in Clinical Settings Intravenous Vitamin B12 is usually used for severe deficiency cases or when quick correction is needed

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