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The tripeptide has high affinity for copper, and most of GHK's documented biological activity in the published literature is mediated by the copper complex particularly its effects on antioxidant enzyme activity, ECM remodeling, and gene expression

[PubMed ID: 10951221]

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However, at higher concentrations (10 mg/dl), uric acid promotes cellular senescence and downregulates EGF/EGFR signaling

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