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(30) Circadian Disruption The activities of your immune cells are affected by your circadian rhythm, a set of biological processes that shape your behavior and physiology and follow a roughly 24-hour cycle

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Moreover, exendin-4 inhibits NF-B activity by hindering the breakdown of IB (NF-kappa-B inhibitor alpha) in LPS-stimulated primary microglia, which reduces the activation of microglia and the generation of pro-inflammatory cytokines [113]

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DOI Miller DM, DeSilva D, Pickart L, Aust SD