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True recovery and symptom management require a holistic approach

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Some mechanisms of motor neuron injury include cytoplasmic protein aggregation [12], pathologic RNA processing, dysregulated microglia with associated neuroinflammation, and oxidative stress, among others [8]

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The relative expression of FAO genes (MCD, CPT1, CPT2, ACADL, ECHS1, ACAA2) was significantly decreased in both OmWAT and ScWAT of B12 deficient women compared with subjects with sufficient levels of B12 (Fig