BioFactors 40(1):2740 Fernndez-Snchez A, Madrigal-Santilln E, Bautista M, Jaime Esquivel-Soto J, Morales-Gonzlez A, Esquivel-Chirino C, Durante-Montiel I, Snchez-Rivera G, Valadez-Vega C, Morales-Gonzlez JA (2011) Inflammation, oxidative stress, and obesity
Menopause accelerates visceral fat accumulation and worsens insulin sensitivity through distinct biological mechanisms
Suggested amount: 2,000 to 4,000 international units (IU) daily for men and women
doi: 10.7150/thno.45922
Heart palpitations appear in some user reports, though less frequently than flushing
Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2-deoxyguanosine) in ex vivo human skin