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The FDA approved the Wegovy pill on December 22, 2025

Minor bruising and slight swelling are normal inflammatory responses that usually fade within 24 hours and do not indicate a problem

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Participants lowered their weight by an average of 28.7 percent (just over 72lbs) and reduced pain by up to an average of 4.5 points, using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score

This represents a fundamental translational gap that must be acknowledged when interpreting the mechanistic evidence presented in this review

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