Chronic blockade of GLP-1R with intra 3rd ventricular infusion of exendin (939) increases food intake and fat mass [700]
They can help rule out other conditions, such as gastroesophageal reflux disease (GERD), suggest a change to your Wegovy dosing schedule , or recommend a different treatment
LY3437943 demonstrated a safety and tolerability profile equivalent to other incretins in a phase 1 single ascending dosage study
Katarzyna Skura, a board-certified physician, specializes in internal medicine and adult primary care
The information is intended to inform and educate
We thank Andreas Brockmeyer, Jenny Borman and Svenja Heimann for support in mass spectrometry measurements, Christine Nowak for protein and plasmid purification, Sasikala Thavam, Nathalie Bleimling, Jens Warmers and Anna Sophie Sickau for technical support