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Instead, it appears to work indirectly by stimulating release of met-enkephalin, one of the body's natural opioid peptides

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For example, in 2008, researchers in China undertook a three-month trial to assess the hypoglycemic effect of berberine versus metformin, a common prescription used to control the blood sugar levels in people with type 2 diabetes

Improving levels may help emotional stability and wellbeing. 9

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